Cell & Gene Therapy Companies in the UK: 66 Active Firms (2026)
Cell and gene therapy companies develop advanced therapies using modified cells, genes or tissue engineering within the UK ATMP framework.
Buying centres tend to sit in translational science, clinical development, GMP manufacturing and analytical quality control, rather than in general corporate procurement. Customers are usually other therapy developers, manufacturers or clinical sponsors that need specialised capacity, manufacturing capability, validated assays or platform support inside the UK ATMP environment. Engagements are usually high-touch and technical: a development collaboration, a manufacturing or import pathway, or a service contract tied to release testing, process development or trial supply. The buying cycle tends to involve scientific, clinical, quality and regulatory teams together, with MHRA expectations shaping the evidence package well before commercial launch.
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At UK level, the cohort comprises 66 actively trading companies, of which 5 report turnover above £5M and 13 were incorporated since 2022. Employment is also concentrated, with total reported headcount of 588 across the firms that disclose staff numbers. The shape is therefore a specialist company universe: therapy developers, manufacturing-service providers, analytical-service teams and enabling-technology businesses, rather than a broad horizontal technology category. A relatively small revenue-scaled layer sits above a younger group still moving through technical, clinical and regulatory milestones.
Cell and gene therapy work falls within the UK ATMP regime. The MHRA is the competent authority for medicinal products and for UK manufacturers or importers of ATMPs; clinical-trial applications go to the MHRA, marketed therapies need authorisation, and manufacturers need a manufacturer’s licence. The regime distinguishes gene therapy medicinal products, somatic cell therapy medicinal products and tissue-engineered products. Where human tissues or cells are used as starting materials, the Human Tissue Authority and Human Fertilisation and Embryology Authority may also be relevant before medicines legislation applies. Market structure follows from that: evidence generation, quality systems and licensed capacity are part of the commercial model, not just compliance overhead.
Commercial progression appears likely to remain uneven. Therapy developers tend to need long technical validation cycles, while service and enabling-technology suppliers can reach revenue earlier through manufacturing, analytics or platform work. Scale-up scarcity is likely to persist because licensing, quality systems and clinical evidence requirements raise the cost of moving from specialist research capability into repeatable commercial delivery. The cohort may also see more partnership and acquisition activity as larger life-science buyers look for capacity, intellectual property or process expertise. Near-term differentiation is likely to rest less on broad discovery claims and more on manufacturability, trial readiness and regulatory execution.
What’s in the file
One row per company, 50+ columns — everything below plus each company’s verified directors, from Companies House filings.
Company data
Verified directors — included
Active director count is the full Companies House board, so it can be higher than the number of names listed — we leave out nominee and formation-agent directors, who aren’t worth contacting. It’s blank for the small number of companies whose officers we haven’t fetched yet.
You’re charged per business, not per row. Where a business trades through several registered companies you get every one, and the Group Primary column marks one row per business — filter to those and the count matches your invoice. Rows sharing a website are not automatically one business: franchises and multi-site operators each count separately, and where names don’t prove a relationship we count them apart rather than guess.
66
Active firms
2026
5
Over £5M turnover
Companies crossing threshold
13
Incorporated since 2022
Newer registrations
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Key facts
About 7% of the trading cohort reports turnover above £5M (5 of 66 firms) — the rest sits below that revenue band.
19% of the cohort was incorporated since 2022 (13 firms), so a sizeable share is in its first few filing cycles.
Cell and gene therapies generally fall within the UK ATMP framework, covering gene therapy medicinal products, somatic cell therapy medicinal products and tissue engineered products under the Human Medicines Regulations 2012.
The MHRA handles ATMP clinical-trial applications, marketing authorisations and manufacturer licensing; the Human Tissue Authority and Human Fertilisation and Embryology Authority may also be relevant where human tissues and cells are starting materials.
UK ATMP investment was £1.7 billion in 2022, £0.77 billion in 2023 and £0.97 billion in 2024, leaving the market below the 2022 peak.
UK ATMP GMP manufacturing facility space reached 51,862 m² in 2024.
The UK had 187 ongoing advanced therapy clinical trials in 2024, up 7% year on year, with Phase I trials rising from 24 to 41.
Top UK Cell & Gene Therapy companies
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Computed from 5 filingsProvides contract development and manufacturing services for cell and gene therapies. Operates GMP-compliant facilities for cell therapy production, process development, quality control testing, and…
Serves biotechnology and pharmaceutical companies developing cell and gene therapies, including organisations needing GMP production scale-up, process development, QC support and ultra-cold storage…
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DistressedDistressed · -54% CAGR over 4y
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Provides contract development and manufacturing services for advanced therapy products including gene therapies, vaccines and immunotherapies. Offers process development, formulation, analytics and…
Serves life-science innovators and advanced therapy developers, including biotech and pharma teams working on gene therapies, immunotherapies, oncolytics and vaccines from research through…
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Computed from 5 filingsProvides contract development and manufacturing services for regenerative medicine. Uses automated iDEM technology to produce cell therapies at scale, supporting cell culture, process and analytical…
Serves clinical-stage regenerative medicine and cell therapy biotech companies developing therapies for areas such as brain, eye, bone, hearing and corneal conditions, particularly teams needing…
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HealthyHealthy · Hiring · 29% CAGR over 4y
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Develops gene therapies for inherited and degenerative eye diseases. Conducts research and clinical trials using adeno-associated virus (AAV) gene therapy to treat conditions such as X‑linked…
Serves patients with inherited and age-related retinal diseases, plus healthcare providers and clinical trial partners involved in ophthalmic gene therapy for XLRP, dry AMD and cone rod dystrophy.
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Develops regenerative macrophage cell therapies for the treatment of inflammatory and fibrotic diseases. Conducts research, development and manufacturing of engineered macrophage-based therapeutics,…
Targets patients with inflammatory and fibrotic diseases, particularly liver cirrhosis, via specialist clinicians, hospitals, trial sites and healthcare systems involved in advanced liver disease…
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Computed from 4 filingsDevelops and manufactures human red blood cells derived from adult stem cells for use as transfusion therapies. Conducts biotechnology research and scalable biomanufacturing to produce clinical‑grade…
Targets healthcare providers, hospitals, blood transfusion services and government or defence agencies serving civilian care, chronic transfusion patients, military settings and emergency stockpiling.
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HealthyHealthy · Hiring · 11% CAGR over 3y
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Develops cancer immunotherapies based on natural killer (NK) cells and small‑molecule compounds. Uses stem cell‑derived and engineered NK cells to create therapeutic candidates targeting…
Targets the oncology market, with future customers and stakeholders including healthcare providers, cancer patients with haematological or solid tumours, and life sciences investors.
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Computed from 3 filingsDevelops personalised T cell therapies for cancer treatment. Uses a platform combining in vivo priming and ex vivo optimisation to create targeted cell therapies designed to recognise…
Serves oncology healthcare and life sciences organisations, including hospitals, research collaborators and commercial partners, with engagement also aimed at specialist investors in T cell therapy.
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HealthyHealthy · Hiring · 73% CAGR over 2y
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Develops cell therapy technologies for cancer treatment, focusing on CAR T‑cell approaches for solid tumours. Conducts research and development of platform technologies and therapeutic candidates,…
Serves cancer patients and oncology care providers, with an initial focus on ovarian cancer and other solid cancer cases where patients have limited treatment options.
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Computed from 4 filingsDevelops synthetic gene promoters and computational design tools to control gene expression for gene therapy, cell therapy and biologics manufacturing. Provides promoter libraries, tissue‑targeted…
Serves biotech and pharmaceutical organisations developing gene and cell therapies, biologics and biomanufacturing platforms, including teams working with tissue-targeted expression, CHO production…
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HealthyHealthy · -59% CAGR over 3y
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Develops gene therapies and delivery technologies targeting neurodegenerative disorders. Conducts research and clinical development of RNA‑silencing and other gene therapy treatments for conditions…
Serves patients and caregivers affected by neurodegenerative and retinal diseases, alongside clinical trial investigators and biopharma partners focused on FTD, ALS, Alzheimer’s/tauopathies and…
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Computed from 5 filingsDevelops genetic medicines and nucleic acid therapies using the Fusogenix PLV delivery platform and fusion protein technology. Focuses on targeted delivery systems that enable precise biodistribution…
Serves biopharma partners, government stakeholders and investors involved in genetic medicine, while ultimately targeting patients and families affected by diseases with unmet clinical needs.
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StrongStrong · Growing · 0% CAGR over 4y
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Computed from 2 filingsDevelops automated bioreactor systems for cell therapy manufacturing, particularly iPSC and other allogeneic cell processes. Technology integrates sensors, control software and perfusion modules to…
Serves biotech and pharma cell therapy developers, CDMOs, process development teams, academic labs and translational researchers scaling iPSC-based and allogeneic therapies from R&D toward clinical…
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StrongStrong · Hiring · 150% CAGR over 1y
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Computed from 5 filingsDevelops software platforms for managing cell and gene therapy supply chains. Provides systems that track patients, materials, manufacturing, and logistics across clinical trials and commercial…
Serves cell and gene therapy developers and other advanced therapy organisations, from clinical trial teams to commercial supply chain stakeholders, including healthcare providers, logistics…
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StableStable · -68% CAGR over 4y
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Develops oncolytic immunotherapies for colorectal cancer. Uses its T‑SIGn platform to create systemically delivered viruses that target tumours and deliver immune‑modulating genes, advancing drug…
Serves people living with colorectal cancer, particularly patients with mismatch repair-proficient locally advanced rectal cancer, alongside clinical trial participants and patient communities.
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Computed from 5 filingsDevelops and supplies synthetic DNA using cell‑free production technology. Provides contract development and manufacturing services and distributed micro‑foundry systems for producing DNA constructs…
Serves biotech and pharmaceutical researchers, therapy and vaccine developers, advanced materials manufacturers, and government partners from discovery through clinical and commercial development.
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StrongStrong · Growing, Hiring · 22% CAGR over 3y
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Computed from 3 filingsDevelops oncolytic virus therapies for cancer treatment. Uses genetically modified adenoviruses and a multi‑modality delivery system to target and destroy tumour cells while stimulating immune…
Targets the oncology healthcare market, with therapies intended for cancer patients, particularly those with solid tumours, and stakeholders involved in clinical development and cancer treatment.
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WeakWeak · 0% CAGR over 2y
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Computed from 5 filingsProcesses, stores and releases stem cells and human tissue products for medical use. Provides cellular therapy processing, biobanking, cord blood and tissue storage, and handling of allografts, along…
Serves public-sector NHS organisations, private clinics, and healthcare or life-science teams working with cellular therapies, allografts, biobanking and related regulated projects.
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HealthyHealthy · -14% CAGR over 4y
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Develops engineered cell-based therapeutic platforms using genome editing and synthetic biology. Programs immune-derived cells to deliver targeted therapeutic payloads such as cytokines, antibodies…
Targets healthcare markets focused on patients with complex diseases, particularly cancer and autoimmune conditions.
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Computed from 3 filingsDevelops gene therapy technologies using plasmid vectors delivered via viral and non‑viral methods to upregulate or downregulate disease‑related genes, targeting conditions including autoimmune,…
Targets large patient populations with serious unmet treatment needs, particularly in autoimmune, neurological, metabolic and infectious diseases, and cancer.
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DistressedDistressed · -15% CAGR over 2y
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Computed from 2 filingsDevelops targeted cancer immunotherapies, including a universal CAR T cell platform and antibody-based treatments targeting the nfP2X7 receptor. Conducts research and development of therapies for…
Targets the oncology healthcare market, with therapies intended for cancer patients suffering from a wide range of liquid and solid tumours worldwide.
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StableStable · 0% CAGR over 1y
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Develops engineered viral vectors for gene therapy using AI modelling and laboratory assays. Focuses on designing adeno-associated virus (AAV) capsids to improve tissue targeting, reduce dosage…
Targets B2B biopharma companies, gene therapy developers and research teams working with AAV or other viral-vector platforms, especially those seeking technical collaborators for preclinical…
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Develops synthetic biology technology to reprogram induced pluripotent stem cells into specific human cell types. Supplies iPSC‑derived cells, disease model cells and CRISPR‑ready cells, and provides…
Serves life sciences researchers in biotech, pharmaceutical and academic labs, especially teams working on drug discovery, disease modelling, CRISPR screening and cell therapy development.
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Computed from 4 filingsDevelops red blood cell‑based therapeutics using engineered cells that carry therapeutic proteins. Operates a biotechnology platform to produce therapeutic red blood cells from cell lines for…
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Computed from 5 filingsDevelops microRNA‑based molecular diagnostic assays and analytical services for cell and gene therapy research and manufacturing. Provides tests for residual pluripotent stem cells, mycoplasma…
Serves B2B customers in pharmaceutical, biotechnology, and cell and gene therapy research, development, and manufacturing, including teams involved in cell therapy characterisation, quality control,…
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StableStable · -5% CAGR over 4y
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Computed from 5 filingsProvides clinical trial services, biobanking, and human tissue sample collection and storage. Develops biomanufacturing capabilities for advanced cell therapies, including stem cell and CAR‑T…
Serves private and NHS hospitals, UK and international biotech and pharmaceutical companies, academic researchers, and government bodies.
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StrongStrong · Growing, Hiring · 29% CAGR over 4y
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Computed from 4 filingsDevelops gene therapy treatments for ophthalmic diseases. Conducts pre‑clinical research and builds a pipeline of bi‑functional gene therapies designed to deliver genetic instructions targeting…
Serves healthcare markets through ophthalmology-focused gene therapy, targeting patients with common eye diseases such as AMD and engaging investors and potential biopharma or research partners for…
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StrongStrong · Hiring · 5% CAGR over 3y
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Computed from 2 filingsDevelops immunotherapy technologies aimed at improving how immune cells recognise and attack disease targets. Focuses on research into T‑cell interactions and technologies designed to enhance the…
Targets biopharmaceutical and cell therapy organisations developing CAR-T and other immunotherapies, alongside research collaborators and partners in immune-cell targeting.
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DistressedDistressed · 0% CAGR over 1y
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Computed from 5 filingsDevelops cell analysis technology for bioprocessing and cell therapy manufacturing. Its AuraCyt‑based Celledonia platform measures intrinsic cell properties without labelling to generate predictive…
Serves biopharmaceutical and cell therapy organisations, particularly bioprocessing and cell line development teams working on monoclonal antibodies, viral vectors, and allogeneic or autologous cell…
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StrongStrong · Hiring · 32% CAGR over 4y
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Computed from 3 filingsDevelops RNA-based genome engineering technology for precise genetic modification. Designs programmable molecular systems that recognise DNA, join strands and synthesise sequences to insert large…
Serves B2B life sciences customers, including genetic medicine and cell/gene therapy developers, industrial biotech teams working with microbes or plants, and organisations exploring non-CRISPR gene…
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StrongStrong · Growing, Hiring · 27% CAGR over 2y
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Computed from 5 filingsDevelops gene therapy technology for treating genetic diseases. Its Gentrafix platform uses replicating plasmid DNA designed to spread between cells and deliver functional gene copies, enabling…
Targets patients affected by genetic diseases with no effective treatments or therapies that are costly, limited in scope, or short-duration; also addresses life-science investors and gene therapy…
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Computed from 3 filingsDevelops gene therapies for genetic ciliopathy disorders including Bardet-Biedl syndrome. Its lead programme uses AAV9 viral vectors to deliver functional BBS1 genes to tissues, aiming to treat…
Targets patients with ciliopathies, especially Bardet-Biedl Syndrome caused by BBS1 mutations, along with caregivers and specialist healthcare communities involved in genetic obesity and blindness.
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Computed from 5 filingsDevelops machine‑learning and generative AI tools to discover and engineer T‑cell receptors (TCRs) for cancer immunotherapies. Uses computational models to analyse TCR sequence space and identify…
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StableStable · Hiring · 11% CAGR over 4y
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Computed from 5 filingsDevelops biotechnology treatments for hair loss, including a follicle banking service that stores hair follicles for future use and cell‑based therapies that culture follicle cells for injection into…
Targets hair transplant clinicians and clinics, clinical partners, and male and female patients with androgenic alopecia seeking hair rejuvenation pathways; also addresses investors in biotech…
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StrongStrong · Growing, Hiring · 4% CAGR over 4y
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Computed from 5 filingsDevelops laboratory manufacturing systems for biologics development and production. Its Qudos platform provides controlled processing, data capture and scalable workflows for applications such as…
Serves biotech and pharmaceutical R&D and manufacturing teams developing advanced biologics, including cell line development, fermentation studies and mRNA therapy programmes, from early labs to…
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HealthyHealthy · Hiring · 6% CAGR over 4y
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Computed from 5 filingsDevelops lipid nanoparticle (LNP) targeting technologies for drug delivery. Its NanoPilot platform engineers LNPs to deliver therapeutics to specific cell types while reducing off‑target liver…
Serves pharmaceutical and biotech companies developing LNP-based therapeutics, including teams seeking licensing opportunities for targeted drug-delivery technologies.
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Computed from 5 filingsDevelops oncolytic virotherapy drugs using engineered viruses to treat cancer and other serious diseases, focusing on therapies intended to target and destroy tumour cells through viral mechanisms.
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Computed from 4 filingsDevelops mRNA-based genetic medicines using proprietary nanocarrier delivery systems, machine learning models, and nucleic acid engineering. Conducts drug discovery and development of therapies…
Targets pharmaceutical and biotech partners and, ultimately, patients with life-threatening diseases, particularly in cancer, lung disease and neurodegenerative disease treatment markets.
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Computed from 5 filingsDevelops regenerative medicine therapies including cell-based treatments designed to promote vascular regeneration and tissue repair. Conducts biomedical research and development focused on…
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DistressedDistressed · -60% CAGR over 4y
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Computed from 5 filingsDevelops nanoparticle-based delivery systems for in vivo cell and gene therapies, enabling targeted transport of genetic payloads such as CRISPR tools to reprogram patient cells. Technology aimed at…
Serves healthcare and life sciences customers developing advanced therapies, particularly cell and gene therapy and cancer immunotherapy programmes. Targets biotech and pharmaceutical R&D teams…
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StableStable · -54% CAGR over 5y
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Computed from 4 filingsDevelops modular immunotherapies for cancer and other diseases using high‑throughput cell screening and machine learning. Generates and tests large libraries of engineered proteins, such as CAR and…
Serves biopharmaceutical and biotech partners developing cancer immunotherapies, especially teams working on modular protein, CAR or BiTE therapies seeking preclinical candidates for clinical…
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StrongStrong · Hiring · 104% CAGR over 3y
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Develops T cell receptor-based immunotherapies for cancer. Uses a proprietary platform and humanised mouse models to identify and generate human T cell receptors that enable drugs designed to direct…
Targets oncology markets, ultimately serving cancer patients and healthcare providers treating tumours; also addresses biopharmaceutical investors and scientific stakeholders in TCR-based…
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Computed from 4 filingsDevelops and manufactures laboratory instruments and automation systems for biologics, gene therapy and nanoparticle research. Products measure protein and nucleic acid concentration, particle size,…
Sells to biologics, gene therapy, cell therapy, genomics and nanoparticle researchers in biotech, pharmaceutical and academic labs, including teams working on antibodies, viral vectors, LNPs,…
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DistressedDistressed · -37% CAGR over 3y
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Computed from 3 filingsDevelops biotechnology for targeted gene delivery, using artificial intelligence to design and optimise systems that transport genetic material into specific cell types for research and potential…
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Computed from 3 filingsDevelops drug delivery systems for the central nervous system, including convection‑enhanced delivery devices for gene and other therapeutics. Provides consultancy, protocol development, training,…
Serves biotech and pharmaceutical companies developing CNS therapies, as well as CROs and clinical trial teams involved in neurological disease programmes.
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Computed from 5 filingsDevelops viral-based cancer immunotherapies using modified oncolytic vaccinia virus technology. Conducts research and preclinical development of systemically deliverable therapies designed to target…
Targets the cancer therapeutics market, ultimately serving oncology patients, including those with metastatic colorectal cancer, through healthcare and clinical development channels.
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Computed from 5 filingsDevelops drug and cell-based therapies targeting gastrointestinal diseases. Its pipeline includes a small‑molecule candidate aimed at preventing bowel cancer by inhibiting abnormal cell growth, and a…
Targets pharmaceutical partners, investors and clinical research stakeholders in gastrointestinal disease, with products aimed at patients with FAP, Crohn’s-related perianal fistulas, IBD and bowel…
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Computed from 5 filingsDevelops cell analysis technology that characterises cells using 3D fluorescence and label‑free imaging data, providing insights for drug discovery research and biotechnology cell manufacturing…
Sells to B2B life sciences customers, including biotech and pharmaceutical R&D teams in drug discovery and organisations involved in cell manufacturing.
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Develops exosome-based drug delivery technologies using engineered stem cell lines. Operates a proprietary platform to produce and customise exosomes with tissue‑targeting properties for use in…
Serves biopharmaceutical companies and therapeutic developers seeking exosome-based targeted delivery platforms, including partners in precision medicine R&D, translational science and licensing…
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Computed from 4 filingsDevelops AI-based software and services for analysing cell imaging data to support development of cell therapies. Provides a cloud platform that predicts cell states and outcomes from images, and…
Serves biotech and cell therapy R&D teams developing cell-based therapeutics, selling to scientists and process development teams that need predictive cell analytics and optimisation support for…
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How UK Cell & Gene Therapy companies work and how to sell to them
What they do
Cell and gene therapy companies usually make money in one of three ways: advancing owned therapeutic assets, selling specialist development or manufacturing services, or licensing enabling technology into other ATMP programmes. Therapy developers tend to be milestone-led businesses, with revenue arriving through collaborations, trial sponsorship arrangements or later-stage licensing rather than ordinary product sales. Service providers are more commercial from the outset, pricing around process development, GMP manufacturing slots, import or release activities and validated analytical work. Engagements are rarely self-serve; they are scoped as technical work packages with quality, regulatory and clinical dependencies.
Who they sell to
Most buyers are themselves therapy developers, clinical sponsors, specialist manufacturers or platform teams that need UK ATMP capability they cannot build quickly in-house. The first conversation is often with a chief scientific officer, head of process development, clinical operations lead or quality director, while finance, legal and procurement join once capacity, liability and regulatory evidence are being committed. Contract size tends to follow risk rather than seat count: a release assay, tech-transfer package or manufacturing campaign is assessed on patient, trial and batch consequences. Direct technical selling is common, with RFPs appearing for larger outsourced manufacturing or trial-supply work.
What they buy
Most cell and gene therapy firms tend to spend on systems and suppliers that protect traceability, quality and evidence. Relevant categories include electronic quality management, document control, laboratory information management, sample tracking, inventory, clinical operations tooling, validation support, cyber security and secure research computing. Manufacturing-led firms also buy cleanroom services, specialist facilities support, cold-chain logistics, GMP consumables, equipment calibration and maintenance, and analytical instrumentation support. Earlier-stage therapy developers tend to need regulatory consulting, biostatistics, trial operations, grant and partnership support, patent advice, finance support and specialist recruitment for clinical, quality, regulatory, process-development and analytical roles.
Why and how to sell to them
Buying intent often appears when a programme moves from research into GMP work, an assay has to be validated, a clinical-trial package is being prepared, or a manufacturing route needs to be insourced, outsourced or transferred. Other triggers include a senior hire in quality or regulatory affairs, a new clinical sponsor relationship, a funding event, a licensing deal, or visible recruitment for manufacturing and analytical roles. Sellers usually need to lead with risk reduction rather than efficiency language: fewer batch-release surprises, clearer chain of custody, cleaner audit trails, better documentation for MHRA-facing work and less rework during tech transfer.
How this list is built
Data sources
This list is built from UK Companies House filings, XBRL accounts data, and semantic analysis of each company's public website. Revenue and headcount figures come from the most recent filed accounts; where the company has not filed, values are estimated using a model trained on filed history and peer benchmarks and are labelled as estimates.
Classification
Rather than relying solely on SIC codes, Firmbase classifies each company semantically: the company's website is crawled, an AI model reads what the company actually sells, and the company is placed into the relevant industry and subsectors. SIC codes are used as one signal but not the only one. This means a company that registered under a generic SIC code but pivoted into (for example) fintech is correctly identified as fintech, not as its original SIC category.
Freshness
The underlying company data is refreshed from Companies House continuously; filings appear in the list within days of submission. The curated list ordering is regenerated when the underlying data moves meaningfully (company count changes by more than 5%, a new company enters the top-ranked segment, or the filed-revenue numbers for the top firms change). You can see the last-updated timestamp near the top of the page.
Related directories
Frequently asked questions
How many Cell & Gene Therapy companies are there in the UK?
What counts as a Cell & Gene Therapy company in this list?
Which are the largest Cell & Gene Therapy companies in the UK?
What do Cell & Gene Therapy companies in the UK actually do?
How does UK Cell & Gene Therapy compare internationally?
How is this list built and how fresh is the data?
How big are the typical Cell & Gene Therapy companies in the UK?
Are these mostly new or established Cell & Gene Therapy companies?
What SIC codes does this use?
What buying signals should I look for?
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